Comparability of Plasma Iohexol Clearance Across Population-Based Cohorts
نویسندگان
چکیده
منابع مشابه
Swine by the Plasma Clearance of Iohexol
There is no simple method to measure glomerular filtration rate (GFR) in swine, an 15 established model to study renal disease. We developed a protocol to measure GFR in conscious 16 swine with the plasma clearance of iohexol. We used two groups: testing and validation, of 8 17 animals each. Ten milliliters of iohexol (6.47 g) were injected by the marginal auricular vein and 18 blood samples (3...
متن کاملConcordance Between Iothalamate and Iohexol Plasma Clearance.
To the Editor: Iohexol is regarded as an accurate filtration marker for measuring GFR. Recently, Soveri et al concluded that plasma clearance of iohexol could be considered a valid alternative to the gold standard, urinary clearance of inulin. Because inulin urinary clearance is cumbersome and costly, iohexol and iothalamate clearance have become popular in Europe and the United States, respect...
متن کاملA Simple Method to Measure Renal Function in Swine by the Plasma Clearance of Iohexol
There is no simple method to measure glomerular filtration rate (GFR) in swine, an established model for studying renal disease. We developed a protocol to measure GFR in conscious swine by using the plasma clearance of iohexol. We used two groups, test and validation, with eight animals each. Ten milliliters of iohexol (6.47 g) was injected into the marginal auricular vein and blood samples (3...
متن کاملIohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 1: How to measure glomerular filtration rate with iohexol?
While there is general agreement on the necessity to measure glomerular filtration rate (GFR) in many clinical situations, there is less agreement on the best method to achieve this purpose. As the gold standard method for GFR determination, urinary (or renal) clearance of inulin, fades into the background due to inconvenience and high cost, a diversity of filtration markers and protocols compe...
متن کاملIohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 2: Why to measure glomerular filtration rate with iohexol?
A reliable assessment of glomerular filtration rate (GFR) is of paramount importance in clinical practice as well as epidemiological and clinical research settings. It is recommended by Kidney Disease: Improving Global Outcomes guidelines in specific populations (anorectic, cirrhotic, obese, renal and non-renal transplant patients) where estimation equations are unreliable. Measured GFR is the ...
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ژورنال
عنوان ژورنال: American Journal of Kidney Diseases
سال: 2020
ISSN: 0272-6386
DOI: 10.1053/j.ajkd.2019.10.008